Section: Research Program

Research axis 4: Evolutionary Systems Biology

This axis, consisting in integrating the two main biological levels we study, is a long-standing and long-term objective in the team. These last years we did not make significant advances in this direction and we even removed this objective from last year's report. However the evolution of the team staff and projects allows us to give it back its central place. We now have the forces and ideas to progress. We have several short and middle term projects to integrate biochemical data and evolution. In particular we are analysing with an evolutionary perspective the 3D conformation of chromosomes, the regulatory landscape of genomes, the chromatin-associated proteins.