Section: Highlights of the Year

Highlights of the Year

• S. Benzekry was nominated expert within the scientific board of the national multi-thematic institute (ITMO) Cancer of the French alliance for health sciences (AVIESAN).

• In collaboration with the experimental team of the SMARTc unit of the Center of Cancer Research of Marseille (CRCM), we published the results of a four-years long study for optimizing the sequence and schedule of antiangiogenic-cytotoxics combinations in the treatment of non-small cell lung cancer [7]. With the objective to determine an optimal interval between the administration of the two types of drugs (currently administered concomitantly in the clinic), we validated a research strategy that consisted in three steps: 1) Initial experiments, 2) Calibration and refinement of a mathematical model adapted to the data and 3) experimental validation of the predictions of the calibrated model (superiority of a 3 days time interval).